Phosphatidylserine Powder

Product Introduction

Phosphatidylserine (PS) is an acidic phospholipid that naturally occurs in the neuronal membrane of the brain. Phosphatidylserine powder is a common dietary supplement that plays an important role in brain function. It is often referred to as the "smart nutrient" and is considered the next important nutrient after choline and DHA, which is also known as "brain gold". PS makes up 17.7% of the brain's phospholipids, making it a crucial component of cell membranes. It is mainly found on the inner side of the cell membrane and is involved in various metabolic activities within cells. Thanks to its lipid-soluble nature, it can easily cross the blood-brain barrier after absorption, promoting vascular smooth muscle cells' relaxation and increasing blood flow to the brain.

Phosphatidylserine (PS) is a phospholipid that is naturally present in cell membranes, particularly in the brain. It plays a crucial role in various physiological processes, including cell signaling, neurotransmitter release, and membrane fluidity. Phosphatidylserine can be derived from both plant and animal sources and is available in powder form as a dietary supplement.

Phosphatidylserine powder has gained attention in the health and wellness industry due to its potential cognitive and mental health benefits.

COA:

Our Phosphatidylserine Products Available

● Water-soluble Phosphatidylserine
Through the encapsulation process, PS can be made completely water-soluble, making it more widely used and easier to absorb. It can also be directly applied to solid beverages.

● Phosphatidylserine Liquid

We use the super extraction process to produce liquid PS, through which the solvent PS is extracted directly into the carrier, guaranteeing good liquid flowability.
This enriches PS's product state. The main application is filling soft gel capsules, thus expanding the product's field of application.

Phosphatidylserine Granular
It solves the main problem of hard capsule filling. The product has the disadvantages of poor fluidity and high viscosity, but granular PS solves the above two most critical problems. It is most suitable for the customers who fill hard capsules.

● Common phosphatidylserine

We have common phosphatidylserine powder that is from sunflower seed and soy two sources.

Product Advantages:

●High fluidity: It has perfect fluidity, which makes it more widely used in practical applications.

●High Content: The highest content of conventional PS can be 75%. We have increased the maximum content to 80% through our special process, for some customers who require higher content. Provide more suitable products, and remove more unknown substances. This can improve the stability of the product.

● We independently researched and developed phospholipase D with advanced technology to ensure stable product quality.
● With freeze crushing technology, the product size is smaller, the fluidity is better, and the viscosity of the finished product is reduced.
● Phosphatidylserine has a wide range of specifications and can be used as a source of soybean and sunflower seeds.
● Oil soluble PS can be used as soft capsule, and the suspension state is stable.
● None-GMO raw material,HPLC-ELSD testing.

Standard Test Procedure Of phosphatidylserine

1. Instrument and reagent

1.1 High performance liquid chromatography: Waters1525 pump; Alltech ELSD2000ES detector; Empower chromatographic workstation.

1.2 Ultrasonic cleaning instrument: power250W, frequency 40KHz

1.3 Analytical balance: Amount of sense 0.00001g

1.4 Volumetric flask(25mL,10 mL)

1.5 Pipette(5mL)

1.6 PC Standard(99%)

1.7 PS Standard(98%)

1.8 n-hexane(chromatographic grade)

1.9 isopropyl alcohol(chromatographic grade)

1.10 acetic acid(analytical grade)

1.11 triethylamine(analytical grade)

2. Chromatographic condition

The chromatographic column Column: Lichrospher Diol 4mm×125mm, 5µm;

The drift tube temperature: 80℃

Gain: 1

Column temperature:45℃

The air flow rate:2.5L/min

Flow rate: 1mL/min;

Injection volume:10µL;

Mobile phase

A: n-hexane:isopropyl alcohol:Acetic acid: triethylamine(815:170: 5: 0.8, V/V)

B: isopropyl alcohol: water: Acetic acid: triethylamine(837.5: 140: 5: 0.8,V/V)

Gradient condition:

3. Solution preparation

3.1 Standard preparation:

Weigh accurately about 10mg of PC and 10mg of PS in 25ml volumetric flask, dissolve and make up the volume with n-hexane: isopropyl alcohol(80:20,V/V),constant volume,get the Standard I, Draw accurately about 5ml Standard I in 10ml volumetric flask,constant volume, get the Standard II.

3.2 Sample preparation:

Weigh accurately about 10mg of test sample in 25ml volumetric flask,dissolve and make up the volume with n-hexane: isopropyl alcohol(80:20,V/V),diluting to volume with n-hexane: isopropyl alcohol.

4. Procedure

In the above chromatography conditions, After the baseline smoothly, inject the Standard I 3 times, peak area relative standard deviation (RSD)<3.0%.Then in the following order into the sample determination:Standard I- sample solution-Standard II- sample solution -Standard I, The retention time of PC is about 10 min, The retention time of PS is about 14 min.

5. Calculation

Using external standard two point method logarithmic equation calculation content.

With the reference substance solution 1 and 2 reference substance solution peak area, the abscissa denotes the logarithm,Reference substance concentration logarithm to establish standards for the vertical curve equation:lgY=a lgX+b,R>0.999,a is the Coefficient,b is the intercept.Sample of the peak area into the equation of the concentration of PS Y of the sample drawn.

PS(%)=Y*V*K/W*100

Y: the concentration of PS and PC mg/mL

V: The amount of dilution of the sample mL

K: The purity of reference substance

W: The sample quantity of the sample mg

Content results samples from two parallel content of sample average.

Functions

1.) Phosphatidylserine can help improve memory, delay brain fatigue, and treat Alzheimer's disease

2.) Phosphatidylserine can assist in the treatment of children with ADHD

3.) Phosphatidylserine can relieve mental stress

4.) Phosphatidylserine can assist in the treatment of depression

5.) Phosphatidylserine can be used as a raw material for sports nutrition.

Application of Product

Phosphatidylserine powder (PS) has a range of potential applications due to its role in cellular function and brain health. Here are some examples of how it can be used:

1. Cognitive support: This powder is often marketed as a nootropic supplement, aimed at enhancing cognitive function, especially memory, attention, and learning. It may improve neurotransmitter activity and signaling between brain cells, leading to increased cognitive performance.

2. Sports nutrition: The powder has been investigated for its potential benefits in sports performance. It may help reduce muscle damage and inflammation, leading to faster recovery, and enhance exercise capacity. It is also believed to promote better stress management, which can be beneficial for athletes.

3. Mood support: Phosphatidylserine supplementation has been associated with improvements in mood and symptoms of depression. It may help regulate neurotransmitters involved in mood regulation, such as dopamine and serotonin.

4. Age-related cognitive decline: Phosphatidylserine has been studied for its potential to reduce age-related cognitive decline, prevent memory loss, and improve mental clarity in the elderly.

5. ADHD: Some studies suggest that phosphatidylserine may be beneficial for children with attention deficit hyperactivity disorder (ADHD) by improving behavior, concentration, and cognitive processing speed.

Third Part Test Result

We have established partnerships with prestigious third-party laboratories, including Eurofins and SGS. Upon customer request, we are capable of arranging reinspection of NAD (Nicotinamide Adenine Dinucleotide) samples prior to shipment. Furthermore, we are fully equipped to coordinate testing with any laboratory designated by the customer to ensure their specific requirements are met.

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OEM Packaging Available

Yangge Biotech Halal certificates

Over the years, we have been committed to the product manufacture optimization and quality system establishment. And we have obtained the Certificate for phosphatidylserine and all our manufactured products.

FAQ

※ Do you have factory?

Yes, we have a 1500m2 factory with modern equipment, welcome to visit our factory. When you have the details schedule, please kindly let me know in advance.

※ Do you have GMP?

All of our products are produced according to GMP standard, meanwhile, we have obtained ISO22000, Halal Certificate and so on.

※ What is your delivery time?

As usual, our delivery time is about 1~3 days after receipt of payments, however, for some special products, please kindly confirm with your sales manager in advance.

※ How can you confirm your quality?

Each batch of the goods can be shipped to you after strict inspection, if you still doubt, we can arrange the Pre-shipment Samples to your testing or to your pointed third party for retesting in advance, successfully, then we will arrange the bulk goods to you immediately.

Technological Process

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Exhibitions

We often attend international exhibitions, including CPhI, FIC, API, Vitafoods, SupplesideWest.

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Yangge Biotech Factory

- All goods are manufactured in GMP standard facilities.

- All goods are released after inspection by our independent laboratory or third party.

- All goods are transported by professional freight companies.

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For phosphatidylserine powder there are different specification for your choice, we can provide 10-30g of free samples, US warehouse in stock of 500kg of each month for the market of the global. certificate of analysis (COA), MSDS, specification sheet, pricing quotation is obtainable upon your request.

If you have any question or need any documents, welcome to contact us by e-mail: info@yanggebiotech.