Berberine Hydrochloride
Product Name: Berberine Hydrochloride
Appearance: Yellow crystalline powder
Specifications: 98%
Part Used: Whole Plant
Test Method: HPLC, UV
OEM Packaging Available
No Irradiation, Non-GMO, Non-Allergen
Comply with Europe standard of PAH4, Benzopyrene ≤10 ppb
Cooperation with famous laboratory for retesting
Min Order: 1Kg
Storage: Store in tightly closed original container, protected from light
Package: 1Kg/Aluminum foil bag or Custom Required
Inventory: 500kg
Brand Name: Yangge
availability: In stock
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Yangge Biotech's Berberine Hydrochloride Powder – Premium Botanical Extract for Blood Sugar & Heart Health
Berberine Hydrochloride (Berberine HCl) is a premium botanical ingredient extracted from plants such as Berberis aristata, Coptis chinensis, and Phellodendron amurense. Widely recognized for its high purity and excellent bioavailability, Berberine Hydrochloride powder is one of the most sought-after ingredients in blood sugar support supplements, weight management formulas, metabolic health products, and cardiovascular wellness supplements.
At Yangge Biotech, we are a trusted berberine hydrochloride manufacturer, berberine hydrochloride supplier, and berberine hydrochloride exporter, providing high-quality bulk Berberine HCl powder for dietary supplements, pharmaceuticals, and functional foods. Our China Berberine HCl powder is manufactured under strict quality control standards to ensure exceptional purity, batch-to-batch consistency, and reliable performance for global brands.
Whether you are developing capsules, tablets, gummies, or other nutraceutical products, Yangge Biotech offers OEM/ODM services, private label solutions, competitive wholesale pricing, and dependable global supply to support your product development and business growth. Contact us here or email us info@yanggebiotech.com
What Is Berberine Hydrochloride?
Berberine is an isoquinoline alkaloid extracted from a variety of plants, including barberry, tree turmeric, goldenseal, Amur cork trees, and the Oregon grape. The roots, stems, and bark are the richest sources of berberine. Berberine has a bitter taste, as is the case for most alkaloids. It is a vibrant yellow color, and dye makers use it to make the pigment Natural Yellow 18.
Berberine hydrochloride is a yellow crystalline powder that is odorless and has a bitter taste. It is highly soluble in water and ethanol. In supplements, berberine hcl is usually standardized to contain 85-99% total alkaloids, of which at least 70% is berberine.
Berberine exhibits potent antibacterial, antiprotozoal, anti-inflammatory, glucose-regulating, cholesterol-lowering, and immune-enhancing effects. It works through multiple mechanisms in the body to achieve these benefits.

COA Of Berberine Hydrochloride Powder
|
Items and Results |
||
|
Object |
Specs. |
Result |
|
Appearance |
Yellow Powder, odorless, bitter taste |
Follow |
|
Identity |
1) Color reaction A: Positive 2) Reaction color B: Positive 3) Reaction color C: Positive 4)IR: Corresponds to IR reference spectrum 5) Chloride: Positive |
Positive Positive Positive Meet the requirements Positive |
|
Loss of Dryness |
≤12.0% |
11.31% |
|
Stay on Ignition |
≤0.2% |
0.04% |
|
Particle Size |
100% to 80mesh |
Competitions |
|
Other alkaloids |
Meet the requirements |
Competitions |
|
Heavy iron |
≤10ppm |
Competitions |
|
Pb |
≤0.5ppm |
Competitions |
|
As |
≤1ppm |
Competitions |
|
Hg |
≤0.1ppm |
Competitions |
|
CD |
≤0.5ppm |
Competitions |
|
Total Number of Plates |
≤1000cfu/g |
Competitions |
|
Yeast and Molds |
≤100cfu/g |
Competitions |
|
E. coli |
Negative |
Negative |
|
Salmonella |
Negative |
Negative |
|
essay |
≥ 97% |
97.5%% |
|
Conclusion: According to the specification. |
||
|
Shelf Life and Storage: 2 years. Keep container unopened in a cool, dry place. |
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Berberine Hydrochloride Mechanisms Of Actions
Primary mechanisms of action of berberine include:
● Inhibiting bacterial cell adhesion and intracellular replication
● Stimulating AMP-actuated protein kinase( AMPK), which regulates metabolism and energy homeostasis
● cranking up the LDL receptor, which removes LDL cholesterol from the blood
● Delayed absorption of carbohydrates in the intestine
● Reducing inflammation by inhibiting inflammatory cytokines

What Does Berberine Hydrochloride Do?
People use premium berberine hcl 98% for a variety of reasons.
1. Anti-Inflammatory. Berberine exhibits anti-inflammatory properties, which help alleviate inflammation throughout the body. This can be beneficial against conditions due to chronic inflammation.
2. Gut. Berberine acts as an antimicrobial agent, balancing gut flora and addressing issues like bacterial overgrowth, which supports digestive health and alleviates gastrointestinal discomfort.
3. Antioxidant. As an antioxidant, berberine scavenges free radicals, protecting cells from oxidative damage. This helps reduce the risk of chronic diseases and supports overall health and vitality.
4. Blood Sugar. Berberine has shown promising results in regulating blood sugar levels by improving hormone sensitivity and reducing it’s resistance.
5. Neuroprotective. Emerging research suggests that berberine may have neuroprotective properties, supporting brain health and cognitive function.
6. Heart. Studies indicate that berberine may help lower cholesterol and triglyceride levels, contributing to improved cardiovascular health. It supports heart function and reduces plaque buildup in arteries.
7. Weight Loss. Berberine can aid in weight loss by boosting metabolism and reducing fat accumulation. It may also suppress appetite, making it a valuable food supplement.
8. Liver Function. Berberine aids in liver detoxification, protecting the liver from toxins and enhancing its function. It may promote liver regeneration.
9. Antimicrobial. Berberine HCl possesses antimicrobial properties, inhibiting the growth of bacteria, viruses, and fungi. It can help treat various infections, including those of the respiratory and urinary tracts.

What Is Berberine Hydrochloride Used For
Pharmaceutical Uses
Berberine is under investigation for development as a drug for diabetes, high cholesterol,
treatment, and more. It shows synergistic effects with pharmaceuticals such as metformin and statins.
Nutraceutical Uses
Berberine is commonly found in capsules, tablets, and powders sold as a natural supplement. It is also added to multivitamins and heart health supplements.
Food and Beverage Uses
Berberine is used as a natural food additive and preservative in several products due to its antimicrobial properties. It is also added to functional foods and beverages.
Industrial Agricultural Uses
Berberine has antifungal, antibacterial, and antiparasitic effects on plants. It is being researched as a potential natural pesticide and fungicide for crops.

Berberine Hydrochloride Side Effects
The most common berberine side effects are gastrointestinal. Some individuals may experience upset stomach, gas, constipation, or diarrhea. Do not take berberine while on antibiotics, as the combination is toxic. Berberine may interact with diabetes medication. Consult with a physician before taking a new supplement.
Reliable Berberine Hydrochloride Factory for OEM & Wholesale Solutions
Yangge Biotech Co., Ltd. is a leading berberine hydrochloride manufacturer, berberine hydrochloride supplier, and berberine hydrochloride exporter, serving dietary supplement, pharmaceutical, and functional food companies worldwide. As one of the established berberine hydrochloride manufacturers and berberine hydrochloride factories in China, we are committed to delivering premium-quality Berberine Hydrochloride (Berberine HCl) powder backed by consistent quality, technical expertise, and dependable global supply.
Yangge Biotech Co., Ltd. China Berberine HCl powder is manufactured from carefully selected raw materials using advanced extraction and purification technologies to achieve exceptional purity, stability, and batch-to-batch consistency. Every production lot undergoes comprehensive quality testing, including HPLC analysis, and is supported by complete technical documentation such as COA, specification sheets, and internationally recognized quality certifications.
As a professional China berberine ingredient supplier, Yangge Biotech Co., Ltd. provide flexible bulk supply solutions for capsules, tablets, gummies, sachets, and other nutraceutical formulations. Whether you are seeking a reliable berberine hydrochloride supplier, sourcing China berberine chloride powder, or partnering with an experienced berberine factory for OEM/ODM and private label manufacturing, Yangge Biotech offers competitive wholesale pricing, stable production capacity, and responsive technical support to help accelerate your product development and global market success. Contact us for inquiry!
Third Part Test Result
We have established partnerships with prestigious third-party laboratories, including Eurofins and SGS. Upon customer request, we are capable of arranging reinspection of Berberine Hydrochloride powder samples prior to shipment. Furthermore, we are fully equipped to coordinate testing with any laboratory designated by the customer to ensure their specific requirements are met.

OEM Packaging Available

Yangge Biotech Halal certificates
Over the years, we have been committed to the product manufacture optimization and quality system establishment. And we have obtained the Certificate for Berberine Hydrochloride and all our manufactured products.

FAQ
※ Do you have factory?
Yes, we have a 1500m2 factory with modern equipment, welcome to visit our factory. When you have the details schedule, please kindly let me know in advance.
※ Do you have GMP?
All of our products are produced according to GMP standard, meanwhile, we have obtained ISO22000, Halal Certificate and so on.
※ What is your delivery time?
As usual, our delivery time is about 1~3 days after receipt of payments, however, for some special products, please kindly confirm with your sales manager in advance.
※ How can you confirm your quality?
Each batch of the goods can be shipped to you after strict inspection, if you still doubt, we can arrange the Pre-shipment Samples to your testing or to your pointed third party for retesting in advance, successfully, then we will arrange the bulk goods to you immediately.
Technological Process

Exhibitions
We often attend international exhibitions, including CPhI, FIC, API, Vitafoods, SupplesideWest.

Yangge Biotech Factory
- All goods are manufactured in GMP standard facilities.
- All goods are released after inspection by our independent laboratory or third party.
- All goods are transported by professional freight companies.

For Berberine Hydrochloride Powder there are different specification for your choice, we can provide 10-30g of free samples, US warehouse in stock of 500kg of each month for the market of the global. certificate of analysis (COA), MSDS, specification sheet, pricing quotation is obtainable upon your request.
If you have any question or need any documents, welcome to contact us by e-mail: info@yanggebiotech.com







