Berberine Hydrochloride

What is Berberine Hydrochloride?

Berberine is an isoquinoline alkaloid extracted from a variety of plants, including barberry, tree turmeric, goldenseal, Amur cork trees, and the Oregon grape. The roots, stems, and bark are the richest sources of berberine. Berberine has a bitter taste, as is the case for most alkaloids. It is a vibrant yellow color, and dye makers use it to make the pigment Natural Yellow 18.

Berberine hydrochloride is a yellow crystalline powder that is odorless and has a bitter taste. It is highly soluble in water and ethanol. In supplements, berberine hcl is usually standardized to contain 85-99% total alkaloids, of which at least 70% is berberine.

Berberine exhibits potent antibacterial, antiprotozoal, anti-inflammatory, glucose-regulating, cholesterol-lowering, and immune-enhancing effects. It works through multiple mechanisms in the body to achieve these benefits.

COA Of Berberine Hydrochloride Powder

Berberine Hydrochloride Mechanisms Of Actions

Primary mechanisms of action of berberine include:

● Inhibiting bacterial cell adhesion and intracellular replication

● Stimulating AMP-actuated protein kinase( AMPK), which regulates metabolism and energy homeostasis

● cranking up the LDL receptor, which removes LDL cholesterol from the blood

● Delayed absorption of carbohydrates in the intestine

● Reducing inflammation by inhibiting inflammatory cytokines

What Does Berberine Hydrochloride Do?

People use premium berberine hcl 98% for a variety of reasons.

1. Anti-Inflammatory. Berberine exhibits anti-inflammatory properties, which help alleviate inflammation throughout the body. This can be beneficial against conditions due to chronic inflammation.

2. Gut. Berberine acts as an antimicrobial agent, balancing gut flora and addressing issues like bacterial overgrowth, which supports digestive health and alleviates gastrointestinal discomfort.

3. Antioxidant. As an antioxidant, berberine scavenges free radicals, protecting cells from oxidative damage. This helps reduce the risk of chronic diseases and supports overall health and vitality.

4. Blood Sugar. Berberine has shown promising results in regulating blood sugar levels by improving hormone sensitivity and reducing it’s resistance.

5. Neuroprotective. Emerging research suggests that berberine may have neuroprotective properties, supporting brain health and cognitive function.

6. Heart. Studies indicate that berberine may help lower cholesterol and triglyceride levels, contributing to improved cardiovascular health. It supports heart function and reduces plaque buildup in arteries.

7. Weight Loss. Berberine can aid in weight loss by boosting metabolism and reducing fat accumulation. It may also suppress appetite, making it a valuable food supplement.

8. Liver Function. Berberine aids in liver detoxification, protecting the liver from toxins and enhancing its function. It may promote liver regeneration.

9. Antimicrobial. Berberine HCl possesses antimicrobial properties, inhibiting the growth of bacteria, viruses, and fungi. It can help treat various infections, including those of the respiratory and urinary tracts.

10. Potentially Anti-Cancerogenic. Studies suggest berberine may inhibit the growth of malignant cells and prevent tumor formation. It shows promise in the prevention and as an adjunctive therapy alongside conventional treatments.

What Is Berberine Hydrochloride Used For

Pharmaceutical Uses

Berberine is under investigation for development as a drug for diabetes, high cholesterol, cancer treatment, and more. It shows synergistic effects with pharmaceuticals such as metformin and statins.

Nutraceutical Uses

Berberine is commonly found in capsules, tablets, and powders sold as a natural supplement. It is also added to multivitamins and heart health supplements.

Food and Beverage Uses

Berberine is used as a natural food additive and preservative in several products due to its antimicrobial properties. It is also added to functional foods and beverages.

Industrial Agricultural Uses

Berberine has antifungal, antibacterial, and antiparasitic effects on plants. It is being researched as a potential natural pesticide and fungicide for crops.

Berberine Hydrochloride Side Effects

The most common berberine side effects are gastrointestinal. Some individuals may experience upset stomach, gas, constipation, or diarrhea. Do not take berberine while on antibiotics, as the combination is toxic. Berberine may interact with diabetes medication. Consult with a physician before taking a new supplement.

Third Part Test Result

We have established partnerships with prestigious third-party laboratories, including Eurofins and SGS. Upon customer request, we are capable of arranging reinspection of NAD (Nicotinamide Adenine Dinucleotide) samples prior to shipment. Furthermore, we are fully equipped to coordinate testing with any laboratory designated by the customer to ensure their specific requirements are met.

​

OEM Packaging Available

Yangge Biotech Halal certificates

Over the years, we have been committed to the product manufacture optimization and quality system establishment. And we have obtained the Certificate for Blueberry extract anthocyanins and all our manufactured products.

FAQ

※ Do you have factory?

Yes, we have a 1500m2 factory with modern equipment, welcome to visit our factory. When you have the details schedule, please kindly let me know in advance.

※ Do you have GMP?

All of our products are produced according to GMP standard, meanwhile, we have obtained ISO22000, Halal Certificate and so on.

※ What is your delivery time?

As usual, our delivery time is about 1~3 days after receipt of payments, however, for some special products, please kindly confirm with your sales manager in advance.

※ How can you confirm your quality?

Each batch of the goods can be shipped to you after strict inspection, if you still doubt, we can arrange the Pre-shipment Samples to your testing or to your pointed third party for retesting in advance, successfully, then we will arrange the bulk goods to you immediately.

Technological Process

​

Exhibitions

We often attend international exhibitions, including CPhI, FIC, API, Vitafoods, SupplesideWest.

​

Yangge Biotech Factory

- All goods are manufactured in GMP standard facilities.

- All goods are released after inspection by our independent laboratory or third party.

- All goods are transported by professional freight companies.

​

For Berberine Hydrochloride Powder there are different specification for your choice, we can provide 10-30g of free samples, US warehouse in stock of 500kg of each month for the market of the global. certificate of analysis (COA), MSDS, specification sheet, pricing quotation is obtainable upon your request.

If you have any question or need any documents, welcome to contact us by e-mail: info@yanggebiotech.